This study determined the effect of an integrated exercise program (coach and family) in three children with Down syndrome to Betterment their motor and cognitive capabilities, especially reaction time and working memory. For this purpose, the integrated exercise training program was applied in three children with Down syndrome, containing two boys (M1, with a chronologic age of 10.3 years and a mental age of 4.7 years M2, with a chronologic age of 14.6 years and a mental age of less than 4 years) and one girl (F1, chronologic age 14.0 years and a mental age of less than 4 years). Betterments in gross motor capability scores were seen after the training period and Greater Betterments in reaction time test were observed for evaluation parameters. There is a near interrelationship between motor and cognitive areas in subjects with uncommon growth. So, there is a requirement to design intervention programs based on the synchronous involvement of child and parents and aimed at promoting an active lifestyle in subjects with Down syndrome.

Background:  Down syndrome is the most common genetic intellectual disability conditions in 1 out of 800 to1000 live births. Adolescents and youth with Down syndrome are unique population on physical fitness factors related to health.

Method: To investigate the factors of physical fitness and physical activity in adolescents and youth with Down syndrome the international and national data bases such as EBSC, Medline, PubMed،Elsevier، Google scholar, SID from 1996 to 2016 were used. In this research, some Persian and English key words like physical fitness, physical activity, Down syndrome, rehabilitation, intellectual disability, muscular strength, muscular endurance, aerobic fitness, balance, agility and flexibility, were used.

Search of resources determined 130 articles that finally 35 articles were considered for the study.

Results: The results indicated that reduced cardio-respiratory capacity, lower level of physical protrusions and physical fitness in people with Down syndrome is significantly common. Related activities to health are also in low rate.

Conclusion: Future studies have to focuses on power tests and exercise programs, procedures of determining physical activities and practical intervention